Species

Therapeutic Area

Highlighted

Spontaneously Hypertensive (SHR) Rat

SHR/NCrl

SHR
AT A GLANCE

Coat Color

Albino

Strain Code

007

Haplotype

RT1k

Ideal For

genetic hypertension, hypertensive drug research, ADHD model, safety and efficacy testing

Produced In

United States
Description

Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure. Brother x sister mating with continued selection for spontaneous hypertension was then started. To NIH in 1966 from Okamoto at F13. To Charles River from NIH in 1973 at F32.