C57BL/6 Mice

C57BL/6 mice are the most used inbred strain in research. Our C57BL/6 mouse colonies are genetically identical within each strain, eliminating genetic differences that could affect research results. Inbred mouse strains exhibit a high degree of uniformity in their inherited characteristics, or phenotypes, which include appearance, behavior, and response to experimental treatments. We couple our International Genetic Standardization (IGS) program with a pyramid mating system designed to maintain the highest levels of genetic uniformity in our C57BL/6 mice. The pyramid mating system ensures that our C57BL/6 mice are genetically identical within each mouse strain.Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH. We also offer the C57BL/6-Aged Mouse, the C57BL/6-Elite Mouse with a VAF/Elite® health profile (bred in US), and the C57BL/6-SOPF Mouse with a SOPF health profile (bred in France). Through our preconditioning services, we are also able to offer DIO (diet-induced obesity) C57BL/6 mice.