Brown Norway Rat

Silvers and Billingham began brother x sister matings with selection for histocompatibility in 1958 from a brown mutation in a stock of wild rats maintained by King and Aptekman in a pen-bred colony of rats trapped from the wild in 1930 by King at the Wistar Institute. To Charles River from Radiobiology Institute, Netherlands in 1976.One key benefit of using the Brown Norway rat in respiratory work is its consistent response in allergic models. Its unique lung immunology and pathophysiology makes it distinctive among rat strains.